ERCC4

Across TCGA cell cohorts, ERCC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,355 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ERCC4-associated GO terms across cancer lineages are Nucleic acid transport, RNA transport, and Establishment of RNA localization. Each is linked with ERCC4 in more than 16 cancer types. Because this analysis shows association rather than direction, both ERCC4-to-partner and partner-to-ERCC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleic acid transport grouped by ERCC4-low versus ERCC4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERCC4→partner) and Y-score (partner→ERCC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nucleic acid transport →	+0.132	+0.873	.005	.001	3	17
OESOPHAGUS	RNA transport →	+0.132	+0.873	.005	.001	3	17
OESOPHAGUS	Establishment of RNA localization →	+0.112	+0.728	.001	.002	3	17
UPPER_AERODIGESTIVE_TRACT	RNA localization →	+0.083	+0.691	<.001	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Nuclear transport →	+0.073	+0.749	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Nucleocytoplasmic transport →	+0.076	+0.850	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,355 associations by consensus.

Nucleic acid transport by ERCC4 expression — OESOPHAGUS

Explore this box plot interactively →