ERCC3

Across TCGA patient cohorts, ERCC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,402 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERCC3-associated proteins across cancer lineages are TSN, MAN2A1, and HNRNPLL. Each is linked with ERCC3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ERCC3-to-partner and partner-to-ERCC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERCC3 versus TSN in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERCC3→partner) and Y-score (partner→ERCC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TSN →	+0.362	+0.530	.002	<.001	3	7
GBM	MAN2A1 →	-0.507	-0.251	<.001	<.001	3	7
HNSC	HNRNPLL →	+0.293	+0.475	<.001	.001	2	8
LSCC	XAB2 →	+0.263	+0.402	<.001	<.001	3	7
LSCC	AQR →	+0.310	+0.411	<.001	<.001	3	6
GBM	NONO →	+0.185	+0.226	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,402 associations by consensus.

ERCC3 vs TSN — OV

Explore this scatter interactively →