ERCC3

Across TCGA cell cohorts, ERCC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,622 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ERCC3-associated GO terms across cancer lineages are Nuclear export, Establishment of RNA localization, and RNA export from nucleus. Each is linked with ERCC3 in more than 18 cancer types. Because this analysis shows association rather than direction, both ERCC3-to-partner and partner-to-ERCC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear export grouped by ERCC3-low versus ERCC3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERCC3→partner) and Y-score (partner→ERCC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Nuclear export →	+0.082	+0.657	<.001	.001	3	19
LUNG_NSCLC_LUSC	Establishment of RNA localization →	+0.089	+0.835	.002	.007	3	17
PANCREAS	RNA export from nucleus →	+0.113	+0.520	<.001	<.001	3	17
SOFT_TISSUE	RNA localization →	+0.086	+0.543	<.001	.001	3	17
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.152	+0.499	<.001	<.001	3	17
LUNG_SCLC	Late viral transcription →	+0.131	+0.476	<.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,622 associations by consensus.

Nuclear export by ERCC3 expression — BLOOD_Lymphoma

Explore this box plot interactively →