Across TCGA patient cohorts, ERC2 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,246 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERC2-associated proteins across cancer lineages are ATXN2L_S496, BICRAL, and ACVRL1_S160. Each is linked with ERC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERC2-to-partner and partner-to-ERC2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERC2→partner) and Y-score (partner→ERC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ATXN2L_S496 →	+1.639	+1.656	.001	.005	3	1
LSCC	BICRAL →	+0.609	+1.995	.002	.002	3	1
LSCC	ACVRL1_S160 →	-1.018	-1.956	<.001	.001	3	1
LSCC	BMPER →	+0.974	+2.475	<.001	<.001	3	1
LSCC	C11orf96_S385 →	+1.346	+1.506	<.001	.003	3	1
LSCC	C1orf198_S173 →	+0.936	+1.563	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,246 associations by consensus.

Exploration

ERC2 survival (RNA) · tumor vs normal (RNA) · all ERC2 data types