ERC1

Across TCGA patient cohorts, ERC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,829 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERC1-associated proteins across cancer lineages are PTMS, USP5, and RBM8A. Each is linked with ERC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ERC1-to-partner and partner-to-ERC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERC1 versus PTMS in LUAD, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERC1→partner) and Y-score (partner→ERC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PTMS →	+0.270	+0.339	.004	.004	3	5
LUAD	USP5 →	+0.284	+0.545	<.001	<.001	3	5
LSCC	RBM8A →	+0.201	+0.349	<.001	<.001	3	4
PDAC	ATN1_S645 →	+0.333	+0.329	.001	.001	3	4
LSCC	ERC1_S17 →	+0.545	+0.593	<.001	<.001	3	4
LSCC	FKBP4 →	+0.487	+0.450	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,829 associations by consensus.

ERC1 vs PTMS — LUAD

Explore this scatter interactively →