ERC1

Across TCGA patient cohorts, ERC1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,327 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ERC1-associated genes across cancer lineages are AKT3, DCLK2, and RASL12. Each is linked with ERC1 in more than 5 cancer types. Because this analysis shows association rather than direction, both ERC1-to-partner and partner-to-ERC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERC1 versus AKT3 in COAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERC1→partner) and Y-score (partner→ERC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	AKT3 →	+1.042	+0.319	<.001	<.001	3	6
BRCA	DCLK2 →	+0.719	+0.236	<.001	<.001	3	6
UCEC	RASL12 →	+0.897	+0.275	.001	<.001	3	5
COAD	CNRIP1 →	+0.973	+0.305	<.001	<.001	3	5
LSCC	GLT8D2 →	+1.210	+0.315	<.001	<.001	3	5
COAD	LRCH2 →	+0.846	+0.310	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,327 associations by consensus.

ERC1 vs AKT3 — COAD

Explore this scatter interactively →