ERBIN

Across TCGA patient cohorts, ERBIN RNA expression is significantly associated with the protein abundance of many other proteins, with 10,754 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ERBIN-associated proteins across cancer lineages are RPS8, RPL24, and RPL6. Each is linked with ERBIN in more than 5 cancer types. Because this analysis shows association rather than direction, both ERBIN-to-partner and partner-to-ERBIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERBIN versus RPS8 in BRCA, with a Pearson correlation of -0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERBIN→partner) and Y-score (partner→ERBIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPS8 →	-0.473	-1.075	<.001	<.001	3	6
GBM	RPL24 →	-0.374	-0.354	.003	.002	3	4
LSCC	RPL6 →	-0.429	-0.291	<.001	.004	3	4
GBM	RPL7 →	-0.443	-0.440	.001	.003	3	4
BRCA	RPL27A →	-0.471	-0.907	<.001	<.001	3	4
BRCA	MANF →	-0.346	-0.498	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,754 associations by consensus.

ERBIN vs RPS8 — BRCA

Explore this scatter interactively →