ERBIN

Across TCGA cell cohorts, ERBIN RNA expression is significantly associated with the go_rna of many other GO terms, with 5,194 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ERBIN-associated GO terms across cancer lineages are Establishment of protein localization to vacuole, Negative regulation of organelle assembly, and Regulation of hippo signaling. Each is linked with ERBIN in more than 13 cancer types. Because this analysis shows association rather than direction, both ERBIN-to-partner and partner-to-ERBIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to vacuole grouped by ERBIN-low versus ERBIN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERBIN→partner) and Y-score (partner→ERBIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Establishment of protein localization to vacuole →	+0.087	+1.063	<.001	<.001	3	14
LARGE_INTESTINE	Negative regulation of organelle assembly →	+0.054	+0.942	<.001	.004	3	14
OESOPHAGUS	Regulation of hippo signaling →	+0.085	+1.017	.001	.001	3	13
BONE	Protein myristoylation →	+0.161	+1.013	<.001	<.001	3	13
STOMACH	Macroautophagy →	+0.074	+1.111	.005	.001	2	13
BONE	Negative regulation of hippo signaling →	+0.081	+0.847	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,194 associations by consensus.

Establishment of protein localization to vacuole by ERBIN expression — BONE

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