ERBB4

Across TCGA patient cohorts, ERBB4 protein abundance is significantly associated with the protein abundance of many other proteins, with 12,478 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERBB4-associated proteins across cancer lineages are DOCK11, ERBB4_T699, and COLGALT1. Each is linked with ERBB4 in more than 3 cancer types. Because this analysis shows association rather than direction, both ERBB4-to-partner and partner-to-ERBB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERBB4 versus DOCK11 in OV, with a Pearson correlation of -0.40.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERBB4→partner) and Y-score (partner→ERBB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DOCK11 →	-0.599	-0.729	<.001	.001	3	4
OV	ERBB4_T699 →	+1.504	+0.806	<.001	.001	3	4
GBM	COLGALT1 →	-0.638	-0.679	<.001	<.001	3	3
BRCA	DDAH1 →	+0.782	+1.194	<.001	<.001	3	3
HNSC	CPSF1 →	-0.245	-1.154	<.001	.001	3	3
GBM	SMARCC1 →	-0.441	-0.525	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,478 associations by consensus.

ERBB4 vs DOCK11 — OV

Explore this scatter interactively →