ERAS

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ERAS RNA expression is significantly associated with the go_rna of many other GO terms, with 7,103 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ERAS-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, Regulation of DNA-directed DNA polymerase activity, and Regulation of protein folding. Each is linked with ERAS in more than 24 cancer types. Because this analysis shows association rather than direction, both ERAS-to-partner and partner-to-ERAS results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERAS→partner) and Y-score (partner→ERAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SCLCNegative regulation of DNA-templated transcription, elongation →+0.099+0.583<.001<.001324
STADRegulation of DNA-directed DNA polymerase activity →+0.067+0.123<.001<.001324
OVRegulation of protein folding →+0.061+0.415<.001<.001324
SCLCPositive regulation of DNA repair →+0.052+0.723<.001<.001324
STADBase-excision repair, gap-filling →+0.061+0.134<.001<.001323
SCLCInternal protein amino acid acetylation →+0.133+0.803<.001<.001323
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,103 associations by consensus.

Exploration