ERAP1

Across TCGA patient cohorts, ERAP1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,808 significant associations in total. ACC shows the largest number of these associations.

The most reproducible ERAP1-associated genes across cancer lineages are SAMD9L, APOL6, and DDX60. Each is linked with ERAP1 in more than 33 cancer types. Because this analysis shows association rather than direction, both ERAP1-to-partner and partner-to-ERAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERAP1 versus SAMD9L in DLBC, with a Pearson correlation of 0.77.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERAP1→partner) and Y-score (partner→ERAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	SAMD9L →	+2.247	+1.150	<.001	<.001	3	34
SKCM	APOL6 →	+1.669	+1.176	<.001	<.001	3	34
SKCM	DDX60 →	+1.687	+1.310	<.001	<.001	3	34
CHOL	MAN2A1 →	+1.518	+1.671	<.001	<.001	3	34
DLBC	AP3B1 →	+1.189	+1.204	<.001	<.001	3	34
KIRP	PRRC1 →	+1.052	+1.416	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,808 associations by consensus.

ERAP1 vs SAMD9L — DLBC

Explore this scatter interactively →