ERAP1

Across TCGA patient cohorts, ERAP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,174 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ERAP1-associated proteins across cancer lineages are UBA7, PSMB7, and PSMB8. Each is linked with ERAP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ERAP1-to-partner and partner-to-ERAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERAP1 versus UBA7 in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERAP1→partner) and Y-score (partner→ERAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UBA7 →	+0.549	+0.814	<.001	<.001	3	7
LSCC	PSMB7 →	-0.353	-0.489	<.001	.001	3	7
BRCA	PSMB8 →	+0.453	+0.651	<.001	<.001	3	7
HNSC	PSMB10 →	+0.651	+0.725	<.001	<.001	3	7
LSCC	TRIM22 →	+0.450	+0.496	.001	<.001	3	7
HNSC	GBP4 →	+0.690	+0.513	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,174 associations by consensus.

ERAP1 vs UBA7 — HNSC

Explore this scatter interactively →