ERAL1

Across TCGA patient cohorts, ERAL1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,720 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ERAL1-associated genes across cancer lineages are ANTXR2, DDR2, and VGLL3. Each is linked with ERAL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ERAL1-to-partner and partner-to-ERAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERAL1 versus ANTXR2 in OV, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERAL1→partner) and Y-score (partner→ERAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ANTXR2 →	-1.084	-0.490	<.001	<.001	3	7
OV	DDR2 →	-1.314	-0.455	.001	<.001	3	7
BRCA	VGLL3 →	-0.943	-0.614	<.001	<.001	3	7
BRCA	HMCN1 →	-1.070	-0.403	<.001	<.001	3	6
BRCA	ABCA6 →	-0.965	-0.562	<.001	<.001	3	6
OV	AKAP13 →	-0.725	-0.349	.004	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,720 associations by consensus.

ERAL1 vs ANTXR2 — OV

Explore this scatter interactively →