ERAL1

Across TCGA cell cohorts, ERAL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,935 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ERAL1-associated GO terms across cancer lineages are DNA replication checkpoint signaling, Positive regulation of mitotic cell cycle, and Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with ERAL1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ERAL1-to-partner and partner-to-ERAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication checkpoint signaling grouped by ERAL1-low versus ERAL1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ERAL1→partner) and Y-score (partner→ERAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA replication checkpoint signaling →	+0.146	+0.547	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitotic cell cycle →	+0.089	+0.843	.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.139	+0.648	<.001	.004	3	13
PANCREAS	Spindle elongation →	+0.199	+0.603	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.181	+0.935	<.001	<.001	3	13
PANCREAS	Lagging strand elongation →	+0.260	+0.475	.005	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,935 associations by consensus.

DNA replication checkpoint signaling by ERAL1 expression — PANCREAS

Explore this box plot interactively →