EQTN

Across TCGA cell cohorts, EQTN RNA expression is significantly associated with the go_rna of many other GO terms, with 1,647 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EQTN-associated GO terms across cancer lineages are Regulation of blood-brain barrier permeability, Regulation of lamellipodium morphogenesis, and Bundle of His cell to Purkinje myocyte communication. Each is linked with EQTN in more than 5 cancer types. Because this analysis shows association rather than direction, both EQTN-to-partner and partner-to-EQTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of blood-brain barrier permeability grouped by EQTN-low versus EQTN-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EQTN→partner) and Y-score (partner→EQTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of blood-brain barrier permeability →	+0.173	+0.115	.003	.003	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of lamellipodium morphogenesis →	+0.090	+0.145	.001	.008	3	5
LUNG_NSCLC_LUAD	Bundle of His cell to Purkinje myocyte communication →	+0.172	+0.088	.007	<.001	3	5
BLOOD_Leukemia	Lipid export from cell →	+0.148	+0.091	<.001	<.001	3	4
BLOOD_Lymphoma	Positive regulation of protein localization to endosome →	+0.061	+0.023	.002	.006	3	4
BLOOD_Leukemia	Regulation of receptor catabolic process →	+0.095	+0.092	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,647 associations by consensus.

Regulation of blood-brain barrier permeability by EQTN expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →