EPYC

Across TCGA patient cohorts, EPYC RNA expression is significantly associated with the protein abundance of many other proteins, with 13,118 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EPYC-associated proteins across cancer lineages are FLNA_S2414, RCN3, and FAP. Each is linked with EPYC in more than 7 cancer types. Because this analysis shows association rather than direction, both EPYC-to-partner and partner-to-EPYC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPYC versus FLNA_S2414 in OV, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPYC→partner) and Y-score (partner→EPYC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FLNA_S2414 →	+0.735	+2.566	<.001	<.001	3	8
OV	RCN3 →	+0.647	+3.188	<.001	<.001	3	7
OV	FAP →	+1.281	+3.496	<.001	<.001	3	7
BRCA	P3H1 →	+0.611	+1.557	<.001	<.001	3	7
OV	SFRP2 →	+1.822	+3.293	<.001	<.001	3	7
OV	ITGA11 →	+0.771	+3.876	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,118 associations by consensus.

EPYC vs FLNA_S2414 — OV

Explore this scatter interactively →