EPYC

Across TCGA cell cohorts, EPYC RNA expression is significantly associated with the go_rna of many other GO terms, with 424 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible EPYC-associated GO terms across cancer lineages are Articular cartilage development, Complement activation, classical pathway, and Inner ear receptor cell differentiation. Each is linked with EPYC in more than 6 cancer types. Because this analysis shows association rather than direction, both EPYC-to-partner and partner-to-EPYC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Articular cartilage development grouped by EPYC-low versus EPYC-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPYC→partner) and Y-score (partner→EPYC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Articular cartilage development →	+0.771	+1.441	<.001	<.001	3	7
SOFT_TISSUE	Complement activation, classical pathway →	+0.765	+1.260	.002	.002	3	4
BREAST	Inner ear receptor cell differentiation →	-0.063	-0.030	.003	.003	3	4
LIVER	Regulation by virus of viral protein levels in host cell →	+0.132	+0.539	<.001	.007	3	4
PANCREAS	Sphingolipid catabolic process →	+0.058	+0.032	.004	.007	3	3
PANCREAS	Oligosaccharide catabolic process →	+0.107	+0.042	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 424 associations by consensus.

Articular cartilage development by EPYC expression — SOFT_TISSUE

Explore this box plot interactively →