EPX

Across TCGA patient cohorts, EPX protein abundance is significantly associated with the RNA expression of many other genes, with 9,943 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPX-associated genes across cancer lineages are LILRB2, CLC, and TNFRSF8. Each is linked with EPX in more than 6 cancer types. Because this analysis shows association rather than direction, both EPX-to-partner and partner-to-EPX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPX versus LILRB2 in GBM, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPX→partner) and Y-score (partner→EPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LILRB2 →	+1.133	+1.580	.007	.002	3	7
COAD	CLC →	+1.759	+0.548	<.001	<.001	3	7
OV	TNFRSF8 →	+0.919	+1.265	<.001	<.001	3	6
OV	CCL11 →	+1.659	+1.221	<.001	<.001	3	6
CCRCC	LILRB5 →	+0.850	+0.854	<.001	<.001	3	5
BRCA	CLEC10A →	+1.265	+1.507	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,943 associations by consensus.

EPX vs LILRB2 — GBM

Explore this scatter interactively →