EPX

Across TCGA patient cohorts, EPX protein abundance is significantly associated with the protein abundance of many other proteins, with 10,673 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EPX-associated proteins across cancer lineages are PRG2, CLC, and PRG3. Each is linked with EPX in more than 9 cancer types. Because this analysis shows association rather than direction, both EPX-to-partner and partner-to-EPX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPX versus PRG2 in HNSC, with a Pearson correlation of 0.79.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPX→partner) and Y-score (partner→EPX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PRG2 →	+1.340	+1.512	<.001	<.001	3	10
OV	CLC →	+1.567	+1.551	<.001	<.001	3	9
OV	PRG3 →	+1.310	+1.334	<.001	<.001	3	9
GBM	RNASE2 →	+0.925	+1.608	.001	<.001	3	8
PDAC	RNASE3 →	+1.033	+1.262	<.001	<.001	3	8
OV	COTL1 →	+0.641	+1.177	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,673 associations by consensus.

EPX vs PRG2 — HNSC

Explore this scatter interactively →