Across TCGA patient cohorts, EPS8L3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,622 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EPS8L3-associated genes across cancer lineages are USH1C, HNF4G, and MUC13. Each is linked with EPS8L3 in more than 3 cancer types. Because this analysis shows association rather than direction, both EPS8L3-to-partner and partner-to-EPS8L3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS8L3→partner) and Y-score (partner→EPS8L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	USH1C →	+3.563	+2.238	<.001	<.001	3	4
LUAD	HNF4G →	+1.500	+1.539	.004	.003	3	4
LUAD	MUC13 →	+5.178	+2.113	<.001	<.001	3	4
LUAD	GPR35 →	+2.137	+2.427	<.001	<.001	3	4
UCEC	PTK6 →	+1.425	+0.814	<.001	.001	3	3
COAD	PDGFRL →	-0.946	-0.578	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,622 associations by consensus.

Exploration

EPS8L3 survival (RNA) · tumor vs normal (RNA) · all EPS8L3 data types