Across TCGA patient cohorts, EPS8L3 mutation is significantly associated with the RNA expression of many other genes, with 3,834 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPS8L3-associated genes across cancer lineages are RNA5SP412, MRPS15, and HROB. Each is linked with EPS8L3 in more than 2 cancer types. Because this analysis shows association rather than direction, both EPS8L3-to-partner and partner-to-EPS8L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS8L3→partner) and Y-score (partner→EPS8L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.555	+2.159	<.001	.001	3	3
UCEC	MRPS15 →	+0.406	+3.742	.002	<.001	3	3
UCEC	HROB →	+0.662	+3.343	<.001	<.001	3	3
UCEC	AUNIP →	+0.780	+2.662	<.001	<.001	3	3
UCEC	FAAP24 →	+0.655	+4.403	<.001	<.001	3	3
COAD	RNU6-709P →	+0.421	+4.821	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,834 associations by consensus.

Exploration

EPS8L3 survival (RNA) · tumor vs normal (RNA) · all EPS8L3 data types