Across TCGA cell cohorts, EPS8L3 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EPS8L3-associated genes across cancer lineages are TNP1, OR2M3, and ETDC. Each is linked with EPS8L3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EPS8L3-to-partner and partner-to-EPS8L3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS8L3→partner) and Y-score (partner→EPS8L3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TNP1 →	+0.160	+4.415	<.001	.007	3	2
BLOOD_Lymphoma	OR2M3 →	+0.016	+3.343	<.001	<.001	3	1
BLOOD_Lymphoma	ETDC →	+0.404	+3.472	<.001	.002	3	1
SKIN	LRRC31 →	+0.020	+3.415	<.001	.004	3	1
SKIN	OR10G2 →	+0.010	+3.700	<.001	.009	3	1
LARGE_INTESTINE	MAGEB4 →	+0.022	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

EPS8L3 survival (RNA) · tumor vs normal (RNA) · all EPS8L3 data types