EPS8L1

Across TCGA pan-cancer cohorts, EPS8L1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated EPS8L1 data layer compared with 24 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EPS8L1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated EPS8L1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, CCRCC, and PDAC are the cancer types where EPS8L1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	III,IV	1.000	0.344	.009	22	view →
CCRCC	DFS	Tertile	II,III,IV	0.398	0.818	.004	21	view →
PDAC	OS	Median	IV	0.381	0.951	.006	12	view →
LSCC	DFS	Tertile	II,III,IV	0.314	1.000	.006	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

EPS8L1–HNSC (OS)

Open the HNSC breakdown →