EPS8L1

Across TCGA patient cohorts, EPS8L1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,725 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EPS8L1-associated genes across cancer lineages are RDH13, GPRC5A, and SCEL. Each is linked with EPS8L1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EPS8L1-to-partner and partner-to-EPS8L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPS8L1 versus RDH13 in HNSC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS8L1→partner) and Y-score (partner→EPS8L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RDH13 →	+0.835	+0.952	<.001	<.001	3	7
BRCA	GPRC5A →	+1.948	+0.658	<.001	<.001	3	6
HNSC	SCEL →	+1.657	+0.629	<.001	<.001	3	6
HNSC	RHBDL2 →	+0.786	+0.731	<.001	<.001	3	6
UCEC	KRT19 →	+1.948	+0.652	<.001	<.001	3	6
UCEC	B3GNT3 →	+1.421	+0.475	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,725 associations by consensus.

EPS8L1 vs RDH13 — HNSC

Explore this scatter interactively →