EPS8

Across TCGA patient cohorts, EPS8 protein abundance is significantly associated with the RNA expression of many other genes, with 13,987 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EPS8-associated genes across cancer lineages are HEBP1, MGP, and IGFBP7. Each is linked with EPS8 in more than 6 cancer types. Because this analysis shows association rather than direction, both EPS8-to-partner and partner-to-EPS8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPS8 versus HEBP1 in BRCA, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPS8→partner) and Y-score (partner→EPS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HEBP1 →	+0.691	+0.334	.004	<.001	3	7
BRCA	MGP →	+1.681	+0.255	<.001	.001	3	6
OV	IGFBP7 →	+1.067	+0.604	<.001	<.001	3	6
HNSC	RNU6-251P →	+1.159	+0.596	<.001	<.001	3	6
BRCA	CYBRD1 →	+1.096	+0.297	<.001	<.001	3	6
BRCA	ASPN →	+1.424	+0.285	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,987 associations by consensus.

EPS8 vs HEBP1 — BRCA

Explore this scatter interactively →