EPRS1

Across TCGA patient cohorts, EPRS1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,932 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EPRS1-associated genes across cancer lineages are DACT3, GNG2, and CD93. Each is linked with EPRS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both EPRS1-to-partner and partner-to-EPRS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPRS1 versus DACT3 in COAD, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPRS1→partner) and Y-score (partner→EPRS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DACT3 →	-0.813	-0.223	<.001	.002	3	8
OV	GNG2 →	-0.686	-0.261	<.001	<.001	3	8
BRCA	CD93 →	-0.782	-0.281	<.001	<.001	3	7
BRCA	DIPK2B →	-0.796	-0.242	<.001	<.001	3	7
UCEC	FEZ1 →	-0.572	-0.222	<.001	<.001	3	7
BRCA	CLEC1A →	-0.631	-0.285	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,932 associations by consensus.

EPRS1 vs DACT3 — COAD

Explore this scatter interactively →