EPPK1

Across TCGA patient cohorts, EPPK1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,530 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EPPK1-associated genes across cancer lineages are PLEKHO1, PTK6, and MROH6. Each is linked with EPPK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EPPK1-to-partner and partner-to-EPPK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPPK1 versus PLEKHO1 in CCRCC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPPK1→partner) and Y-score (partner→EPPK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PLEKHO1 →	-0.558	-0.895	<.001	<.001	3	5
LSCC	PTK6 →	+1.048	+0.574	<.001	<.001	3	5
UCEC	MROH6 →	+1.188	+0.826	<.001	<.001	3	5
HNSC	SDCBP2 →	+0.986	+0.923	<.001	<.001	3	5
HNSC	AHNAK2 →	+1.133	+0.680	.001	.002	3	5
CCRCC	CD72 →	-0.546	-0.518	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,530 associations by consensus.

EPPK1 vs PLEKHO1 — CCRCC

Explore this scatter interactively →