EPN3

Across TCGA patient cohorts, EPN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,073 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EPN3-associated proteins across cancer lineages are EPN3_S182, EPN3_S449, and EPN3_T495. Each is linked with EPN3 in more than 7 cancer types. Because this analysis shows association rather than direction, both EPN3-to-partner and partner-to-EPN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPN3 versus EPN3_S182 in LSCC, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPN3→partner) and Y-score (partner→EPN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EPN3_S182 →	+1.256	+1.189	<.001	<.001	3	8
LSCC	EPN3_S449 →	+1.319	+1.198	<.001	<.001	3	7
BRCA	EPN3_T495 →	+1.270	+1.128	<.001	<.001	3	7
BRCA	RBM47 →	+0.447	+1.075	<.001	<.001	3	6
HNSC	PKP3 →	+0.728	+0.689	<.001	.001	3	5
LSCC	STAP2 →	+0.566	+0.870	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,073 associations by consensus.

EPN3 vs EPN3_S182 — LSCC

Explore this scatter interactively →