EPN3

Across TCGA cell cohorts, EPN3 mutation is significantly associated with the mutation status of many other genes, with 1,621 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EPN3-associated genes across cancer lineages are NOL11, BACH1, and PCDHA2. Each is linked with EPN3 in more than 2 cancer types. Because this analysis shows association rather than direction, both EPN3-to-partner and partner-to-EPN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOL11 grouped by EPN3-low versus EPN3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPN3→partner) and Y-score (partner→EPN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	NOL11 →	+5.247	+4.429	.005	.005	1	3
URINARY_TRACT	BACH1 →	+4.672	+4.672	.001	.001	1	3
URINARY_TRACT	PCDHA2 →	+3.672	+4.307	.004	.004	1	3
LARGE_INTESTINE	TRIOBP →	+1.781	+3.602	.006	.006	1	3
BLOOD_Leukemia	LMTK3 →	+3.145	+3.932	.004	.004	1	3
BLOOD_Leukemia	LINGO1 →	+3.338	+4.083	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,621 associations by consensus.

NOL11 by EPN3 expression — BLOOD_Lymphoma

Explore this box plot interactively →