EPN2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EPN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,153 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPN2-associated proteins across cancer lineages are LLGL1, PPIB, and EVI2B. Each is linked with EPN2 in more than 5 cancer types. Because this analysis shows association rather than direction, both EPN2-to-partner and partner-to-EPN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPN2 versus LLGL1 in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPN2→partner) and Y-score (partner→EPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCLLGL1 →+0.311+0.714<.001<.00136
BRCAPPIB →-0.362-0.604<.001.00335
GBMEVI2B →-0.548-0.533<.001<.00135
LSCCFMNL1_S624 →-0.557-0.611.005<.00135
LSCCFXR2 →+0.291+0.649<.001<.00135
GBMHTATIP2 →-0.545-0.546<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,153 associations by consensus.

EPN2 vs LLGL1 — LSCC

Per-sample scatter of EPN2 vs LLGL1 in LSCC (Pearson r = 0.37).

Explore this scatter interactively →

Exploration