EPN2

Across TCGA patient cohorts, EPN2 mutation is significantly associated with the RNA expression of many other genes, with 2,722 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPN2-associated genes across cancer lineages are RN7SL785P, RN7SKP261, and RNU6-901P. Each is linked with EPN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both EPN2-to-partner and partner-to-EPN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL785P grouped by EPN2-low versus EPN2-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPN2→partner) and Y-score (partner→EPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RN7SL785P →	+0.408	+3.861	.002	.004	3	3
COAD	RN7SKP261 →	+0.372	+4.484	<.001	.002	3	3
KIRC	RNU6-901P →	+0.262	+8.025	<.001	.007	3	2
SKCM	PSMA6 →	+0.472	+3.246	.008	.008	3	2
SKCM	DHDDS →	+0.487	+3.542	.005	.002	3	2
SKCM	CEP85 →	+0.676	+3.516	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,722 associations by consensus.

RN7SL785P by EPN2 expression — STAD

Explore this box plot interactively →