EPN2

Across TCGA cell cohorts, EPN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,348 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPN2-associated GO terms across cancer lineages are Schwann cell development, Negative regulation of transcription initiation by RNA polymerase II, and Negative regulation of DNA-templated transcription initiation. Each is linked with EPN2 in more than 13 cancer types. Because this analysis shows association rather than direction, both EPN2-to-partner and partner-to-EPN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Schwann cell development grouped by EPN2-low versus EPN2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPN2→partner) and Y-score (partner→EPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Schwann cell development →	+0.124	+1.272	<.001	<.001	3	14
STOMACH	Negative regulation of transcription initiation by RNA polymerase II →	+0.149	+1.371	.005	.002	3	14
STOMACH	Negative regulation of DNA-templated transcription initiation →	+0.149	+1.371	.005	.002	3	14
STOMACH	Regulation of translation at synapse, modulating synaptic transmission →	+0.170	+1.602	<.001	<.001	3	13
OESOPHAGUS	Endosomal transport →	+0.078	+1.084	<.001	<.001	3	13
STOMACH	Pallium development →	+0.074	+0.942	<.001	.007	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,348 associations by consensus.

Schwann cell development by EPN2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →