EPN2-AS1

Across TCGA pan-cancer cohorts, EPN2-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated EPN2-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher EPN2-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated EPN2-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and SKCM show a favorable association.

BRCA, MESO, and LIHC are the cancer types where EPN2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	III,IV	0.638	0.365	.003	48	view →
MESO	DFS	Quartile	IV	0.107	0.426	.001	41	view →
LIHC	DFS	Quartile	All	0.185	0.338	.013	27	view →
SKCM	OS	Tertile	II,III,IV	0.798	0.606	.016	23	view →
CHOL	DFS	Tertile	All	0.663	0.206	.021	21	view →
GBM	OS	Median	All	0.549	0.283	.001	18	view →
UVM	DFS	Tertile	III,IV	0.227	0.672	<.001	16	view →
UCS	OS	Tertile	IV	0.992	0.507	.017	12	view →
BLCA	OS	Tertile	IV	0.391	0.582	.025	9	view →
KICH	DFS	Median	III,IV	1.000	0.516	.021	6	view →
LAML	DFS	Median	All	0.694	0.446	.015	6	view →
UCEC	OS	Median	IV	0.832	0.599	.037	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

EPN2-AS1–BRCA (DFS)

Open the BRCA breakdown →