EPN1

Across TCGA patient cohorts, EPN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,700 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EPN1-associated proteins across cancer lineages are ZBTB7A_S549, MYH14, and MYH14_T1462. Each is linked with EPN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both EPN1-to-partner and partner-to-EPN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPN1 versus ZBTB7A_S549 in LUAD, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPN1→partner) and Y-score (partner→EPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZBTB7A_S549 →	-0.376	-0.404	.002	<.001	3	3
CCRCC	MYH14 →	+0.359	+0.252	.004	.002	3	3
CCRCC	MYH14_T1462 →	+0.811	+0.318	<.001	.001	3	3
PDAC	PARD6B →	+0.395	+0.265	<.001	<.001	3	3
LUAD	PIK3R4_S853 →	-0.626	-0.389	.001	.002	2	4
LSCC	TSEN34 →	+0.259	+0.470	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,700 associations by consensus.

EPN1 vs ZBTB7A_S549 — LUAD

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