EPN1

Across TCGA cell cohorts, EPN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,703 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EPN1-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Regulation of Golgi inheritance, and Regulation of RNA polymerase II transcription preinitiation complex assembly. Each is linked with EPN1 in more than 16 cancer types. Because this analysis shows association rather than direction, both EPN1-to-partner and partner-to-EPN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by EPN1-low versus EPN1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPN1→partner) and Y-score (partner→EPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.078	+1.005	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.176	+1.094	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.148	+1.031	<.001	.001	3	14
BONE	CAMP/PKA signal transduction →	+0.191	+1.110	<.001	<.001	3	14
SKIN	Regulation of protein localization to endoplasmic reticulum →	+0.134	+1.382	<.001	<.001	3	14
BONE	Regulation of modification of postsynaptic structure →	+0.140	+1.019	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,703 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by EPN1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →