EPN1

Across TCGA cell cohorts, EPN1 mutation is significantly associated with the mutation status of many other genes, with 2,286 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EPN1-associated genes across cancer lineages are STARD9, GPATCH8, and IPO4. Each is linked with EPN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EPN1-to-partner and partner-to-EPN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STARD9 grouped by EPN1-low versus EPN1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPN1→partner) and Y-score (partner→EPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	STARD9 →	+4.584	+3.942	.002	.002	1	5
BREAST	GPATCH8 →	+4.297	+4.857	.009	.009	1	4
BREAST	IPO4 →	+4.297	+4.857	.009	.009	1	4
LUNG_NSCLC_LUAD	CUL1 →	+4.772	+5.339	.004	.004	1	4
BLOOD_Leukemia	ZNF689 →	+3.038	+3.347	.002	.002	1	4
BLOOD_Leukemia	MRTFA →	+3.523	+3.662	<.001	<.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,286 associations by consensus.

STARD9 by EPN1 expression — STOMACH

Explore this box plot interactively →