EPM2AIP1

Across TCGA pan-cancer cohorts, EPM2AIP1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated EPM2AIP1 data layer compared with 27 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher EPM2AIP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated EPM2AIP1 expression acts as an unfavorable survival marker.

LGG, PRAD, and UCEC are the cancer types where EPM2AIP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.173	0.810	<.001	12	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
COAD	OS	Median	All	0.516	0.873	.015	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

EPM2AIP1–LGG (OS)

Open the LGG breakdown →