EPM2A

Across TCGA patient cohorts, EPM2A RNA expression is significantly associated with the protein abundance of many other proteins, with 18,495 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPM2A-associated proteins across cancer lineages are TNS1, PPP1R12B, and PTPN1. Each is linked with EPM2A in more than 4 cancer types. Because this analysis shows association rather than direction, both EPM2A-to-partner and partner-to-EPM2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPM2A versus TNS1 in COAD, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPM2A→partner) and Y-score (partner→EPM2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TNS1 →	+0.530	+0.287	<.001	.002	3	5
CCRCC	PPP1R12B →	+0.594	+0.256	<.001	<.001	3	5
CCRCC	PTPN1 →	-0.421	-0.279	<.001	.001	3	5
HNSC	UTRN →	+0.287	+0.591	<.001	<.001	3	5
HNSC	CAP2 →	+0.720	+0.559	<.001	<.001	3	5
LSCC	SPIN1 →	+0.409	+0.358	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,495 associations by consensus.

EPM2A vs TNS1 — COAD

Explore this scatter interactively →