EPHX2

Across TCGA patient cohorts, EPHX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,064 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EPHX2-associated proteins across cancer lineages are MTUS1, CCAR2, and GSR. Each is linked with EPHX2 in more than 5 cancer types. Because this analysis shows association rather than direction, both EPHX2-to-partner and partner-to-EPHX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHX2 versus MTUS1 in LUAD, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX2→partner) and Y-score (partner→EPHX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTUS1 →	+0.460	+0.544	<.001	<.001	3	6
OV	CCAR2 →	+0.359	+0.827	<.001	<.001	3	5
BRCA	GSR →	+0.390	+0.941	<.001	<.001	3	5
BRCA	CCAR2_S678 →	+0.616	+0.929	<.001	<.001	3	5
PDAC	MTM1 →	+0.279	+0.679	<.001	<.001	3	5
GBM	SH2D4A →	+0.476	+0.789	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,064 associations by consensus.

EPHX2 vs MTUS1 — LUAD

Explore this scatter interactively →