EPHX2

Across TCGA patient cohorts, EPHX2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,713 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EPHX2-associated genes across cancer lineages are KIF14, HJURP, and CENPO. Each is linked with EPHX2 in more than 6 cancer types. Because this analysis shows association rather than direction, both EPHX2-to-partner and partner-to-EPHX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHX2 versus KIF14 in BRCA, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX2→partner) and Y-score (partner→EPHX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIF14 →	-0.899	-0.673	<.001	<.001	3	7
BRCA	HJURP →	-0.895	-0.480	<.001	<.001	3	7
COAD	CENPO →	-0.525	-0.509	<.001	.002	3	7
LUAD	CKAP2L →	-0.988	-0.533	<.001	<.001	3	7
BRCA	IQGAP3 →	-1.099	-0.558	<.001	.001	3	7
GBM	TUBB →	-0.707	-0.618	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,713 associations by consensus.

EPHX2 vs KIF14 — BRCA

Explore this scatter interactively →