EPHX2

Across TCGA cell cohorts, EPHX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,101 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPHX2-associated GO terms across cancer lineages are Aerobic respiration, Sulfur compound metabolic process, and Purine ribonucleoside triphosphate metabolic process. Each is linked with EPHX2 in more than 12 cancer types. Because this analysis shows association rather than direction, both EPHX2-to-partner and partner-to-EPHX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by EPHX2-low versus EPHX2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX2→partner) and Y-score (partner→EPHX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Aerobic respiration →	+0.103	+1.550	<.001	<.001	3	13
LARGE_INTESTINE	Sulfur compound metabolic process →	+0.042	+1.147	<.001	<.001	3	12
OVARY	Purine ribonucleoside triphosphate metabolic process →	+0.084	+1.393	<.001	.005	3	12
LIVER	Branched-chain amino acid metabolic process →	+0.105	+2.532	.002	.001	3	11
OVARY	Regulation of myoblast fusion →	+0.122	+1.725	<.001	<.001	3	11
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.110	+1.412	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,101 associations by consensus.

Aerobic respiration by EPHX2 expression — OVARY

Explore this box plot interactively →