EPHX1

Across TCGA patient cohorts, EPHX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,118 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EPHX1-associated proteins across cancer lineages are PRDX6, NAXE, and IARS2. Each is linked with EPHX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both EPHX1-to-partner and partner-to-EPHX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHX1 versus PRDX6 in GBM, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX1→partner) and Y-score (partner→EPHX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRDX6 →	+0.331	+0.410	.001	.001	3	7
PDAC	NAXE →	+0.325	+0.420	<.001	<.001	3	6
UCEC	IARS2 →	+0.312	+0.616	<.001	<.001	3	6
UCEC	GSR →	+0.576	+1.048	<.001	<.001	3	6
UCEC	IDH1 →	+0.757	+1.176	<.001	<.001	3	5
HNSC	TRIP4 →	-0.271	-1.296	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,118 associations by consensus.

EPHX1 vs PRDX6 — GBM

Explore this scatter interactively →