EPHX1

Across TCGA patient cohorts, EPHX1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,356 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible EPHX1-associated genes across cancer lineages are ENTPD3, SERINC5, and CEP70. Each is linked with EPHX1 in more than 4 cancer types. Because this analysis shows association rather than direction, both EPHX1-to-partner and partner-to-EPHX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHX1 versus ENTPD3 in LSCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX1→partner) and Y-score (partner→EPHX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ENTPD3 →	+1.148	+0.707	<.001	<.001	3	5
UCEC	SERINC5 →	+0.573	+0.599	.002	.001	3	5
LUAD	CEP70 →	+1.016	+0.770	<.001	<.001	3	4
LSCC	OSGIN1 →	+1.626	+0.542	<.001	<.001	3	4
HNSC	EPS8 →	+0.784	+0.448	<.001	<.001	3	4
GBM	BUB1B →	-1.214	-0.405	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,356 associations by consensus.

EPHX1 vs ENTPD3 — LSCC

Explore this scatter interactively →