EPHX1

Across TCGA cell cohorts, EPHX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,882 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EPHX1-associated GO terms across cancer lineages are Epoxide metabolic process, Monocarboxylic acid catabolic process, and Lysosomal lumen acidification. Each is linked with EPHX1 in more than 17 cancer types. Because this analysis shows association rather than direction, both EPHX1-to-partner and partner-to-EPHX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epoxide metabolic process grouped by EPHX1-low versus EPHX1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHX1→partner) and Y-score (partner→EPHX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Epoxide metabolic process →	+0.697	+1.986	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Monocarboxylic acid catabolic process →	+0.072	+2.186	.001	<.001	3	12
SOFT_TISSUE	Lysosomal lumen acidification →	+0.119	+1.720	<.001	.005	2	12
LUNG_NSCLC_LUAD	Primary alcohol metabolic process →	+0.120	+1.638	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Unsaturated fatty acid metabolic process →	+0.145	+1.804	<.001	<.001	3	11
CNS	Fatty acid beta-oxidation →	+0.081	+1.685	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,882 associations by consensus.

Epoxide metabolic process by EPHX1 expression — SOFT_TISSUE

Explore this box plot interactively →