EPHB6

Across TCGA patient cohorts, EPHB6 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,547 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPHB6-associated proteins across cancer lineages are CRMP1, SNCG, and ENPP4. Each is linked with EPHB6 in more than 4 cancer types. Because this analysis shows association rather than direction, both EPHB6-to-partner and partner-to-EPHB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHB6 versus CRMP1 in LSCC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHB6→partner) and Y-score (partner→EPHB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CRMP1 →	+0.862	+1.062	<.001	<.001	3	5
UCEC	SNCG →	+1.082	+0.697	<.001	.006	3	4
BRCA	ENPP4 →	-0.474	-1.235	<.001	<.001	3	4
CCRCC	TMF1 →	-0.267	-0.543	<.001	<.001	3	4
UCEC	TWF1 →	-0.377	-0.929	<.001	<.001	3	4
UCEC	CNRIP1 →	+0.722	+0.713	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,547 associations by consensus.

EPHB6 vs CRMP1 — LSCC

Explore this scatter interactively →