EPHB6

Across TCGA patient cohorts, EPHB6 protein abundance is significantly associated with the RNA expression of many other genes, with 16,172 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EPHB6-associated genes across cancer lineages are BTNL9, GPD1, and NSUN6. Each is linked with EPHB6 in more than 1 cancer types. Because this analysis shows association rather than direction, both EPHB6-to-partner and partner-to-EPHB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHB6 versus BTNL9 in GBM, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHB6→partner) and Y-score (partner→EPHB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BTNL9 →	+1.056	+0.720	<.001	<.001	3	2
GBM	GPD1 →	+1.307	+0.435	<.001	<.001	3	2
LUAD	NSUN6 →	+0.685	+0.864	.004	.006	3	2
GBM	LGI4 →	+0.776	+0.404	<.001	.001	3	2
GBM	TPD52L1 →	+0.838	+0.615	<.001	<.001	3	2
CCRCC	MACROD2 →	+1.855	+0.742	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,172 associations by consensus.

EPHB6 vs BTNL9 — GBM

Explore this scatter interactively →