Across TCGA cell cohorts, EPHB4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,696 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EPHB4-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Nucleic acid transport, and RNA transport. Each is linked with EPHB4 in more than 12 cancer types. Because this analysis shows association rather than direction, both EPHB4-to-partner and partner-to-EPHB4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHB4→partner) and Y-score (partner→EPHB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.157	+1.459	.001	<.001	3	13
BONE	Nucleic acid transport →	+0.080	+1.317	.001	<.001	3	12
BONE	RNA transport →	+0.080	+1.317	.001	<.001	3	12
BONE	Nuclear export →	+0.098	+1.812	<.001	<.001	3	12
KIDNEY	Regulation of protein localization to nucleus →	+0.079	+1.465	<.001	<.001	3	11
BONE	Establishment of RNA localization →	+0.076	+1.345	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,696 associations by consensus.

Exploration

EPHB4 survival (RNA) · tumor vs normal (RNA) · all EPHB4 data types