EPHB3

Across TCGA patient cohorts, EPHB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,786 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EPHB3-associated proteins across cancer lineages are PCYT1A, PTPRC_S994, and DMXL1. Each is linked with EPHB3 in more than 4 cancer types. Because this analysis shows association rather than direction, both EPHB3-to-partner and partner-to-EPHB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHB3 versus PCYT1A in LSCC, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHB3→partner) and Y-score (partner→EPHB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PCYT1A →	+0.567	+1.532	<.001	<.001	3	5
GBM	PTPRC_S994 →	-0.642	-0.689	<.001	<.001	3	5
BRCA	DMXL1 →	-0.167	-1.055	.003	<.001	3	5
LSCC	ACTL6A →	+0.318	+1.098	<.001	<.001	3	5
LSCC	FMNL1_S184 →	-0.832	-1.151	<.001	<.001	3	5
LSCC	BIN2 →	-0.507	-1.378	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,786 associations by consensus.

EPHB3 vs PCYT1A — LSCC

Explore this scatter interactively →