EPHB2

Across TCGA patient cohorts, EPHB2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,311 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EPHB2-associated genes across cancer lineages are SORCS2, MIR4684, and CAPN13. Each is linked with EPHB2 in more than 3 cancer types. Because this analysis shows association rather than direction, both EPHB2-to-partner and partner-to-EPHB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHB2 versus SORCS2 in LSCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHB2→partner) and Y-score (partner→EPHB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SORCS2 →	+0.857	+0.387	<.001	.001	3	4
HNSC	MIR4684 →	+1.004	+0.516	.001	<.001	3	4
LSCC	CAPN13 →	+1.431	+0.410	<.001	.006	3	3
UCEC	CXCL1 →	+1.688	+0.498	.002	.001	3	3
LSCC	RBMS1P1 →	+0.734	+0.511	.001	<.001	3	3
OV	NTM →	+1.511	+0.548	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,311 associations by consensus.

EPHB2 vs SORCS2 — LSCC

Explore this scatter interactively →