EPHB2

Across TCGA patient cohorts, EPHB2 protein abundance is significantly associated with the protein abundance of many other proteins, with 17,843 significant associations in total. GBM shows the largest number of these associations.

The most reproducible EPHB2-associated proteins across cancer lineages are EPHB2_S776, TRMT112, and EPHB2_S575. Each is linked with EPHB2 in more than 6 cancer types. Because this analysis shows association rather than direction, both EPHB2-to-partner and partner-to-EPHB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EPHB2 versus EPHB2_S776 in LSCC, with a Pearson correlation of 0.78.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EPHB2→partner) and Y-score (partner→EPHB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EPHB2_S776 →	+1.590	+0.636	<.001	<.001	3	7
OV	TRMT112 →	-0.683	-0.535	.002	.001	3	5
HNSC	EPHB2_S575 →	+1.637	+0.845	<.001	<.001	3	5
GBM	PTBP1 →	-0.174	-0.350	<.001	<.001	3	5
UCEC	CEBPB →	+0.448	+0.737	<.001	<.001	3	4
CCRCC	ARFGAP3 →	-0.328	-0.494	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,843 associations by consensus.

EPHB2 vs EPHB2_S776 — LSCC

Explore this scatter interactively →